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Principal Research Strengths

Research Divisions

Advancing biotechnology through rigorous applied research, green nanotechnology, mosquito vector control, cancer nanoplatforms, and computational discovery.

Division 01

Plant-Mediated Nanotechnology & Phytochemistry

25 Documented Plants

A major component of laboratory research is the utilization of medicinal and biologically important plants for green synthesis of silver (Ag), copper oxide (CuO), zinc oxide (ZnO), and gold (Au) nanoparticles. Documented research and student projects have involved 25 key plant species:

1. Aegle marmelos
2. Ayapana triplinervis
3. Manilkara hexandra
4. Ageratina adenophora
5. Senna alata
6. Cestrum aurantiacum
7. Tiliacora triandra
8. Causonis trifolia
9. Gymnema sylvestre
10. Tagetes erecta
11. Wattakaka volubilis
12. Curcuma longa
13. Allium cepa
14. Bauhinia tomentosa
15. Hibiscus cannabinus
16. Sida acuta
17. Hybanthus enneaspermus
18. Bixa orellana
19. Andrographis paniculata
20. Butea monosperma
21. Murraya koenigii
22. Rubia cordifolia
23. Woodfordia fruticosa
24. Persicaria lapathifolia
25. Orthosiphon aristatus
Division 02

Endophytic Fungi & Myconanotechnology

SBRTL has pioneered myconanotechnology platforms using endophytic fungi isolated from medicinal plants to synthesize AgNPs, CuO NPs, TiO₂ NPs, MoO₃ NPs, and MgO NPs.

1. Trichoderma viride & AgNPs

Extracellular fabrication of silver nanoparticles from Solanum lycopersicum endophytes.

2. Corynespora smithii ZM-1 & CuO NPs

Mycosynthesis of redox-active copper oxide nanoparticles from Ziziphus mauritiana.

3. Aegle marmelos & TiO₂ NPs

Biosynthesis of titanium oxide nanoparticles using endophytic fungal strains.

4. Ayapana triplinervis & MoO₃ / MgO NPs

Myco-engineered molybdenum oxide and magnesium oxide nanoplatforms.

Division 03

Mosquito Vector Biology & Biocontrol

One of SBRTL’s longest-standing research programmes, focusing on eco-friendly vector control strategies against major disease vectors:

pest_control

Aedes aegypti

Dengue & Chikungunya Vector

pest_control

Aedes albopictus

Asian Tiger Mosquito

pest_control

Culex quinquefasciatus

Lymphatic Filariasis Vector

pest_control

Anopheles stephensi

Urban Malaria Vector

Assay Specializations: Larvicidal & pupicidal bioassays, adult repellent activity, oviposition deterrence, and seasonal breeding habitat surveys across Thanjavur & Kumbakonam.
Division 04

Biomedical Nanotechnology & Cancer Research

Transitioning conventional green nanoparticles into functionalized nanoplatforms for targeted therapies with enhanced efficacy and reduced toxicity:

01. Methyl Ionone-PEG-CuO

PEG-functionalized CuO nanoparticles loaded with methyl ionone.

02. Naringenin-PEG-CuO

PEGylated copper oxide nanoplatforms with enhanced antioxidant bioactivity.

03. Morin-Nanoalloy-rGO

Morin-loaded nanoalloy-reduced graphene oxide nanoplatforms.

04. Hes-Au/rGONCs for TNBC

Hesperetin-capped gold-rGO nanocomposites targeting triple-negative breast cancer.

Division 05

Environmental Biotechnology & Microalgae

Development of microalgal bioremediation systems using Chlorella vulgaris for industrial wastewater treatment, textile dye biodegradation, and reverse-osmosis (RO) concentrate demineralization.

Division 06

Bioinformatics & Computational Biology

In-silico molecular docking, molecular dynamics (MD) simulations, structure-activity relationships (SAR), and target prediction. Notable study: Investigating bioactive constituents of Artemisia pallens against efflux proteins of multidrug-resistant Acinetobacter baumannii.